The Effect of Polymorphisms of the β2-Adrenergic Receptor on the Response to Regular Use of Albuterol in Asthma

Israel, Elliot; M. Drazen, Jeffrey; B. Liggett, Stephen; A. Boushey, Homer; M. Cherniack, Reuben; M. Chinchilli, Vernon; M. L. Cooper, David; V. FAHY, JOHN; E. Fish, James; G. Ford, Jean; Kraft, Monica; J. Kunselman, Susan; C. Lazarus, Stephen; F. Lemanske, Robert; J. Martin, Richard; E. McLean, Diane; P. Peters, Stephen; K. Silverman, Edwin; A. Sorkness, Christine; J. Szefler, Stanley; T. Weiss, Scott; Yandava, Chandri

doi:10.1164/ajrccm.162.1.9907092

Public

The Effect of Polymorphisms of the β2-Adrenergic Receptor on the Response to Regular Use of Albuterol in Asthma

Published in American Journal of Respiratory and Critical Care Medicine • Jul 1, 2000

Authors:

Elliot Israel

Jeffrey M. Drazen

Stephen B. Liggett

Abstract

Inhaled beta-adrenergic agonists are the most commonly used medications for the treatment of asthma although there is evidence that regular use may produce adverse effects in some patients. Polymorphisms of the beta(2)-adrenergic receptor (beta(2)-AR) can affect regulation of the receptor. Smaller s...

Subject

Salbutamol

Medicine

Asthma

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