The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.

AM, Gulick; VJ, Starai; AR, Horswill; KM, Homick; JC, Escalante-Semerena

doi:10.1021/bi0271603

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The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.

Shared by NobleBlocks on Mar 1, 2003 • 12:00 AM UTC

Authors:

Gulick AM

Starai VJ

Horswill AR

Abstract

Acetyl-coenzyme A synthetase catalyzes the two-step synthesis of acetyl-CoA from acetate, ATP, and CoA and belongs to a family of adenylate-forming enzymes that generate an acyl-AMP intermediate. This family includes other acyl- and aryl-CoA synthetases, firefly luciferase, and the adenylation domai...

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