Complement C3 Variant and the Risk of Age-Related Macular Degeneration

R.W. Yates, John; Sepp, Tiina; K. Matharu, Baljinder; C. Khan, Jane; A. Thurlby, Deborah; Shahid, Humma; Clayton, David; Hayward, Caroline; Morgan, Joanne; F. Wright, Alan; Maria Armbrecht, Ana; Dhillon, Baljean; J. Deary, Ian; Redmond, Elizabeth; C. Bird, Alan; T. Moore, Anthony

doi:10.1056/nejmoa072618

Public

Complement C3 Variant and the Risk of Age-Related Macular Degeneration

Published in New England Journal of Medicine • Jul 19, 2007

Authors:

John R.W. Yates

Tiina Sepp

Baljinder K. Matharu

Abstract

BACKGROUND: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors. Complement activation is implicated in the pathogenesis. METHODS: We tested for an association between age-related ...

Subject

Macular degeneration

Complement (music)

Degeneration (medical)

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