5-methylcytosine in RNA: detection, enzymatic formation and biological functions

Motorin, Yuri; Lyko, Frank; Helm, Mark

doi:10.1093/nar/gkp1117

Public

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

Published in Nucleic Acids Research • Dec 8, 2009

Authors:

Yuri Motorin

Frank Lyko

Mark Helm

Abstract

The nucleobase modification 5-methylcytosine (m(5)C) is widespread both in DNA and different cellular RNAs. The functions and enzymatic mechanisms of DNA m(5)C-methylation were extensively studied during the last decades. However, the location, the mechanism of formation and the cellular function(s)...

Subject

Biology

5-Methylcytosine

RNA

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