Alterations in behavior, amyloid p‐42, caspase‐3, and Cox‐2 in mutant PS2 transgenic mouse model of Alzheimer's disease

Youn Hwang, Dae; Ryong Chae, Kab; Sun Kang, Tae; Hee Hwang, Jin; Hyung Lim, Chae; Ki Kang, Hyun; Seo Goo, Jun; R. Lee, Mi; J. Lim, Hwa; H. Min, Sae; Y. Cho, Jun; Tae Hong, Jin; Won Song, Chi; Gi Paik, Sang; S. Cho, Jung; K. Kim, Yong

doi:10.1096/fj.01-0732com

Public

Alterations in behavior, amyloid p‐42, caspase‐3, and Cox‐2 in mutant PS2 transgenic mouse model of Alzheimer's disease

Published in The FASEB Journal • Jun 1, 2002

Authors:

Dae Youn Hwang

Kab Ryong Chae

Tae Sun Kang

Abstract

ABSTRACT Alzheimer's disease (AD) occurs when neurons in the memory and cognition regions of the brain are accompanied by an accumulation of the long amyloid p‐proteins of the 39 to 43 amino acids derived from the amyloid precursor protein (APP) by cleavage with p‐and γ‐secretase. An increased produ...

Subject

Genetically modified mouse

Western blot

Enolase

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