Safety and efficacy of recombinant hirudin (CGP 39 393) versus heparin in patients with stable angina undergoing coronary angioplasty.

A. van den Bos, Arjan; W. Deckers, Jaap; R. Heyndrickx, Guy; Laarman, GertJan; Suryapranata, Harry; Zijlstra, Felix; Close, Philippe; J. M. M. Rijnierse, J.; R. Büller, H.; W. Serruys, Patrick

doi:10.1161/01.cir.88.5.2058

Public

Safety and efficacy of recombinant hirudin (CGP 39 393) versus heparin in patients with stable angina undergoing coronary angioplasty.

Published in Circulation • Nov 1, 1993

Authors:

Arjan A. van den Bos

Jaap W. Deckers

Guy R. Heyndrickx

Abstract

BACKGROUND: Enhanced thrombin activity has been associated with acute and long-term complications following balloon angioplasty (percutaneous transluminal coronary angioplasty (PTCA). We evaluated, in a 2-to-1 randomized, double-blind trial, the effects of recombinant hirudin, CGP 39 393, relative t...

Subject

Medicine

Partial thromboplastin time

Heparin

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