Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes.

M, Bandopadhyay; A, Banerjee; N, Sarkar; R, Panigrahi; S, Datta; A, Pal; SP, Singh; A, Biswas; S, Chakrabarti; R, Chakravarty

doi:10.1186/1471-2407-14-721

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Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes.

Shared by NobleBlocks on Sep 26, 2014 • 12:00 AM UTC

Authors:

Bandopadhyay M

Banerjee A

Sarkar N

Abstract

Background Hepatitis B Virus (HBV) X protein (HBx) is known to be involved in the initiation and progression of hepatocellular carcinoma (HCC) through modulation of host gene response. Alterations in miRNA expressions are frequently noted in HCC. This study is aimed to examine the role of HBx protei...

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