Nanoemulsion gel-based topical delivery of an antifungal drug:<i>in vitro</i>activity and<i>in vivo</i>evaluation

Hussain, Afzal; Samad, Abdus; Kumar Singh, Sandeep; Neyaz Ahsan, Mohd; Haque, Md.Wasimul; Faruk, Abdul; Jalees Ahmed, Farhan

doi:10.3109/10717544.2014.933284

Public

Nanoemulsion gel-based topical delivery of an antifungal drug:in vitroactivity andin vivoevaluation

Published in Drug Delivery • Jul 11, 2014

Authors:

Afzal Hussain

Abdus Samad

Sandeep Kumar Singh

Abstract

OBJECTIVE: In this study, attempt has been focused to prepare a nanoemulsion (NE) gel for topical delivery of amphotericin B (AmB) for enhanced as well as sustained skin permeation, in vitro antifungal activity and in vivo toxicity assessment. MATERIALS AND METHODS: A series of NE were prepared usin...

Subject

In vivo

Pharmacology

Amphotericin B

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