Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

Marzolini, Catia; Telenti, Amalio; A. Décosterd, Laurent; Greub, Gilbert; Biollaz, Jérôme; Buclin, Thierry

doi:10.1097/00002030-200101050-00011

Public

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

Published in AIDS • Jan 1, 2001

Authors:

Catia Marzolini

Amalio Telenti

Laurent A. Décosterd

Abstract

OBJECTIVE: Limited information exists on the clinical usefulness of drug level monitoring for efavirenz, a once-daily non-nucleoside reverse transcriptase inhibitor (NNRTI). The aim of this study was to determine whether efavirenz plasma concentration monitoring could predict treatment failure and c...

Subject

Efavirenz

Reverse-transcriptase inhibitor

Tolerability

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