Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer

Vergote, Ignace; G. Tropé, Claes; Amant, Frédéric; B. Kristensen, Gunnar; Ehlen, Tom; Johnson, Nick; H.M. Verheijen, René; E.L. van der Burg, Maria; J. Lacave, Ángel; Benedetti Panici, Pierluigi; G. Kenter, Gemma; Casado, Antonio; Mendiola, César; Coens, Corneel; Verleye, Leen; Stuart, Gavin; Pecorelli, Sërgio; Reed, N.S.

doi:10.1056/nejmoa0908806

Public

Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer

Published in New England Journal of Medicine • Sep 1, 2010

Authors:

Ignace Vergote

Claes G. Tropé

Frédéric Amant

Abstract

BACKGROUND: Primary debulking surgery before initiation of chemotherapy has been the standard of care for patients with advanced ovarian cancer. METHODS: We randomly assigned patients with stage IIIC or IV epithelial ovarian carcinoma, fallopian-tube carcinoma, or primary peritoneal carcinoma to pri...

Subject

Medicine

Ovarian cancer

Chemotherapy

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