Nocturnal Rapid Eye Movement Sleep Latency for Identifying Patients With Narcolepsy/Hypocretin Deficiency

Andlauer, Olivier; Moore, Hyatt; Jouhier, Laura; L. Drake, Christopher; E. Peppard, Paul; Han, Fang; Hong, Seung-Chul; Poli, Francesca; Plazzi, Giuseppe; O’Hara, Ruth; Haffen, Émmanuel; Roth, Thomas; Young, Terry; Mignot, Emmanuel

doi:10.1001/jamaneurol.2013.1589

Public

Nocturnal Rapid Eye Movement Sleep Latency for Identifying Patients With Narcolepsy/Hypocretin Deficiency

Published in JAMA Neurology • May 17, 2013

Authors:

Olivier Andlauer

Hyatt Moore

Laura Jouhier

Abstract

IMPORTANCE: Narcolepsy, a disorder associated with HLA-DQB1*06:02 and caused by hypocretin (orexin) deficiency, is diagnosed using the Multiple Sleep Latency Test (MSLT) following nocturnal polysomnography (NPSG). In many patients, a short rapid eye movement sleep latency (REML) during the NPSG is a...

Subject

Narcolepsy

Polysomnography

Multiple Sleep Latency Test

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