Neurostimulation for Parkinson's Disease with Early Motor Complications

Michael Schuepbach, W.M.; Rau, Jörn; Knudsen, Karina; Volkmann, Jens; Krack, Paul; Timmermann, Lars; D. Hälbig, Thomas; Hesekamp, Helke; Navarro, Soledad; Meier, Niklaus; Falk, Daniela; Maximilian Mehdorn, H.; Paschen, Steffen; Maarouf, Mohammed; T. Barbe, Michael; R. Fink, Gereon; Kupsch, Andreas; Gruber, Doreen; Schneider, Gerd‐Helge; Seigneuret, Éric; Kistner, Andrea; Chaynes, Patrick; Ory‐Magne, Fabienne; Brefel Courbon, Christine; Vesper, Jan; Schnitzler, Alfons; Wojtecki, Lars; Houéto, J.L.; Bataille, B.; Maltête, David; Damier, Philippe; Raoul, Sylvie; Sixel-Doering, F.; Hellwig, D.; Gharabaghi, Alireza; Krüger, Rejko; Pinsker, M.; Amtage, F.; Marcos Gomes Regis, João; Witjas, Tatiana; Thobois, Stéphane; Mertens, Patrick; Kloss, M.; Hartmann, A.; H. Oertel, Wolfgang; Post, Bart; Speelman, Hans; Agid, Yves; Schade‐Brittinger, Carmen; Deuschl, Günther

doi:10.1056/nejmoa1205158

Public

Neurostimulation for Parkinson's Disease with Early Motor Complications

Published in New England Journal of Medicine • Feb 13, 2013

Authors:

W.M. Michael Schuepbach

Jörn Rau

Karina Knudsen

Abstract

BACKGROUND: Subthalamic stimulation reduces motor disability and improves quality of life in patients with advanced Parkinson's disease who have severe levodopa-induced motor complications. We hypothesized that neurostimulation would be beneficial at an earlier stage of Parkinson's disease. METHODS:...

Subject

Dyskinesia

Medicine

Neurostimulation

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