Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors

M. J. Nielen, Markus; van Schaardenburg, Dirkjan; W. Reesink, H.; J. van de Stadt, Rob; van der Horst‐Bruinsma, Irene; H. M. T. De Koning, Margret; R. Habibuw, Moud; P. Vandenbroucke, Jan; A. C. Dijkmans, Ben

doi:10.1002/art.20018

Public

Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors

Published in Arthritis & Rheumatism • Feb 1, 2004

Authors:

Markus M. J. Nielen

Dirkjan van Schaardenburg

H. W. Reesink

Abstract

OBJECTIVE: Autoantibodies have been demonstrated in single serum samples from healthy subjects up to 10 years before they developed rheumatoid arthritis (RA). However, the time course for the development of antibodies before onset of clinical RA is unknown, nor is it known which antibody, or combina...

Subject

Medicine

Rheumatoid factor

Autoantibody

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