ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

Bouatia-Naji, Nabila; Meyre, David; Lobbens, Stéphane; Séron, Karin; Fumeron, Frédéric; Balkau, Beverley; Heude, Barbara; Jouret, Béatrice; E. Scherer, Philipp; Dina, Christian; Weill, Jacques; Froguel, Philippe

doi:10.2337/diabetes.55.02.06.db05-0971

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ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

Shared by NobleBlocks on Feb 1, 2006 • 12:00 AM UTC

Authors:

Nabila Bouatia-Naji

David Meyre

Stéphane Lobbens

Abstract

Common single nucleotide polymorphisms (SNPs) in the ACDC adiponectin encoding gene have been associated with insulin resistance and type 2 diabetes in several populations. Here, we investigate the role of SNPs −11,377C>G, −11,391G>A, +45T>G, and +276G>T in 2,579 French Caucasians (1,229 morbidly ob...

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