Fludarabine, Cyclophosphamide, and Mitoxantrone as Initial Therapy of Chronic Lymphocytic Leukemia: High Response Rate and Disease Eradication

Bosch, Francesc; Ferrer, Ana; Villamor, Neus; González, Marcos; Briones, Javier; González‐Barca, Eva; Abella, Eugènia; Gardella, Santiago; Escoda, Lourdes; Pérez‐Ceballos, Elena; Asensi, Antoni; José Sayas, Ma; Font, Llorenç; Altés, Albert; Muntañola, Ana; Bertazzoni, Paola; Rozman, Marı́a; Aymerich, Marta; Giné, Eva; Montserrat, Emili

doi:10.1158/1078-0432.ccr-07-1371

Public

Fludarabine, Cyclophosphamide, and Mitoxantrone as Initial Therapy of Chronic Lymphocytic Leukemia: High Response Rate and Disease Eradication

Published in Clinical Cancer Research • Jan 1, 2008

Authors:

Francesc Bosch

Ana Ferrer

Neus Villamor

Abstract

PURPOSE: Fludarabine, cyclophosphamide, and mitoxantrone (FCM) results in a high response rate in previously treated patients with chronic lymphocytic leukemia (CLL). The aim of this study was to investigate FCM as frontline therapy in CLL. EXPERIMENTAL DESIGN: Sixty-nine patients under the age of 6...

Subject

Fludarabine

Mitoxantrone

Medicine

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