Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.

Anna K, Coussens,; Robert J, Wilkinson,; Yasmeen, Hanifa,; Vladyslav, Nikolayevskyy,; Paul T, Elkington,; Kamrul, Islam,; Peter M, Timms,; Timothy R, Venton,; Graham H, Bothamley,; Geoffrey E, Packe,; Mathina, Darmalingam,; Robert N, Davidson,; Heather J, Milburn,; Lucy V, Baker,; Richard D, Barker,; Charles A, Mein,; Leena, Bhaw-Rosun,; Rosamond, Nuamah,; Douglas B, Young,; Francis A, Drobniewski,; Christopher J, Griffiths,; Adrian R, Martineau,

doi:10.1073/pnas.1200072109

Public

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.

Published in Proceedings of the National Academy of Sciences of the United States of America • Sep 18, 2012

Authors:

Coussens, Anna K

Wilkinson, Robert J

Hanifa, Yasmeen

Abstract

Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol concentrations, and thus has a potential role in the prevention and treatment of infection. The immunomodulatory effe...

Subject

Adult

Antimicrobial Cationic Peptides

Antitubercular Agents

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!