Lactate is a Preferential Oxidative Energy Substrate over Glucose for Neurons in Culture

The authors investigated concomitant lactate and glucose metabolism in primary neuronal cultures using 13 C- and 1 H-NMR spectroscopy. Neurons were incubated in a medium containing either [1- 13 C]glucose and different unlabeled lactate concentrations, or unlabeled glucose and different [3- 13 C]lac... View More