Dectin-1 Is A Major β-Glucan Receptor On Macrophages

D. Brown, Gordon; R. Taylor, Philip; M. Reid, Delyth; A. Willment, Janet; L. Williams, David; Martínez‐Pomares, Luisa; Y. C. Wong, Simon; Gordon, Siamon

doi:10.1084/jem.20020470

Public

Dectin-1 Is A Major β-Glucan Receptor On Macrophages

Published in The Journal of Experimental Medicine • Jul 29, 2002

Authors:

Gordon D. Brown

Philip R. Taylor

Delyth M. Reid

Abstract

Zymosan is a beta-glucan- and mannan-rich particle that is widely used as a cellular activator for examining the numerous responses effected by phagocytes. The macrophage mannose receptor (MR) and complement receptor 3 (CR3) have historically been considered the major macrophage lectins involved in ...

Subject

Zymosan

Mannose receptor

Receptor

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