Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss

Cancello, Raffaella; Hénégar, Corneliu; Viguerie, Nathalie; Taleb, Soraya; Poitou, Christine; Rouault, Christine; Coupaye, Muriel; Pelloux, Véronique; Hugol, Danielle; Bouillot, Jean-Luc; Bouloumié, Anne; Barbatelli, Giorgio; Cinti, Saverio; Svensson, Per‐Arne; S. Barsh, Gregory; Zucker, Jean‐Daniel; Basdevant, Arnaud; Langin, Dominique; Clément, Karine

doi:10.2337/diabetes.54.8.2277

Public

Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss

Published in Diabetes • Aug 1, 2005

Authors:

Raffaella Cancello

Corneliu Hénégar

Nathalie Viguerie

Abstract

In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is enriched in macrophages. These cells may contribute to low-grade inflammation and to its metabolic complications. Little is known about the effect of weight loss on macrophages and genes involved in macrophage attr...

Subject

Adipose tissue

Adipose tissue macrophages

CD68

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