Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

B. Weksler, B.; A. Subileau, E.; Perrière, N.; Charneau, P.; Holloway, K.; Leveque, M.; Tricoire‐Leignel, H.; Nicotra, A.; Bourdoulous, S.; Turowski, P.; K. Male, D.; Roux, F.; Greenwood, J.; A. Romero, I.; O. Couraud, P.

doi:10.1096/fj.04-3458fje

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Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

Shared by NobleBlocks on Sep 1, 2005 • 12:00 AM UTC

Authors:

B. B. Weksler

E. A. Subileau

N. Perrière

Abstract

ABSTRACT Establishment of a human model of the blood‐brain barrier has proven to be a difficult goal. To accomplish this, normal human brain endothelial cells were transduced by lentiviral vectors incorporating human telomerase or SV40 T antigen. Among the many stable immortalized clones obtained by...

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