Fluconazole Prophylaxis of Fungal Infections in Patients with Acute Leukemia: Results of a Randomized Placebo-Controlled, Double-Blind, Multicenter Trial

J. Winston, Drew; Chandrasekar, Pranatharthi; M. Lazarus, Hillard; L. Goodman, Jesse; L. Silber, Jeffrey; W. Horowitz, Harold; K. Shadduck, Richard; S. Rosenfeld, Craig; G. Ho, Winston; Z. Islam, Muhammed; N. Buell, Donald

doi:10.7326/0003-4819-118-7-199304010-00003

Public

Fluconazole Prophylaxis of Fungal Infections in Patients with Acute Leukemia: Results of a Randomized Placebo-Controlled, Double-Blind, Multicenter Trial

Published in Annals of Internal Medicine • Apr 1, 1993

Authors:

Drew J. Winston

Pranatharthi Chandrasekar

Hillard M. Lazarus

Abstract

OBJECTIVE: To evaluate the efficacy and safety of fluconazole for prevention of fungal infections. DESIGN: A randomized, placebo-controlled, double-blind, multicenter trial. PATIENTS: Adults (257) undergoing chemotherapy for acute leukemia. INTERVENTION: Patients were randomly assigned to receive ei...

Subject

Fluconazole

Medicine

Placebo

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