Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Wu, Yi-Mi; Su, Fengyun; Kalyana‐Sundaram, Shanker; A. Khazanov, Nickolay; Ateeq, Bushra; Cao, Xuhong; J. Lonigro, Robert; Vats, Pankaj; Wang, Rui; Lin, Su‐Fang; Cheng, Ann‐Joy; P. Kunju, Lakshmi; Siddiqui, Javed; A. Tomlins, Scott; Wyngaard, Peter; Sadis, Seth; Roychowdhury, Sameek; Hussain, Maha; Y. Feng, Felix; M. Zalupski, Mark; Talpaz, Moshe; J. Pienta, Kenneth; R. Rhodes, Daniel; R. Robinson, Dan; M. Chinnaiyan, Arul

doi:10.1158/2159-8290.cd-13-0050

Public

Identification of Targetable FGFR Gene Fusions in Diverse Cancers

Published in Cancer Discovery • Apr 4, 2013

Authors:

Yi-Mi Wu

Fengyun Su

Shanker Kalyana‐Sundaram

Abstract

Abstract Through a prospective clinical sequencing program for advanced cancers, four index cases were identified which harbor gene rearrangements of FGFR2, including patients with cholangiocarcinoma, breast cancer, and prostate cancer. After extending our assessment of FGFR rearrangements across mu...

Subject

Identification (biology)

Gene

Computational biology

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