Identification of targetable FGFR gene fusions in diverse cancers.

YM, Wu; F, Su; S, Kalyana-Sundaram; N, Khazanov; B, Ateeq; X, Cao; RJ, Lonigro; P, Vats; R, Wang; SF, Lin; AJ, Cheng; LP, Kunju; J, Siddiqui; SA, Tomlins; P, Wyngaard; S, Sadis; S, Roychowdhury; MH, Hussain; FY, Feng; MM, Zalupski; M, Talpaz; KJ, Pienta; DR, Rhodes; DR, Robinson; AM, Chinnaiyan

doi:10.1158/2159-8290.cd-13-0050

Public

Identification of targetable FGFR gene fusions in diverse cancers.

Shared by NobleBlocks on Apr 4, 2013 • 12:00 AM UTC

Authors:

Wu YM

Su F

Kalyana-Sundaram S

Abstract

Through a prospective clinical sequencing program for advanced cancers, four index cases were identified which harbor gene rearrangements of FGFR2, including patients with cholangiocarcinoma, breast cancer, and prostate cancer. After extending our assessment of FGFR rearrangements across multiple tu...

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