Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials

Moore, Andrew; Makinson, Geoffrey; Li, Chunming

doi:10.1186/ar4134

Public

Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials

Published in Arthritis Research & Therapy • Jan 8, 2013

Authors:

Andrew Moore

Geoffrey Makinson

Chunming Li

Abstract

INTRODUCTION: Although the safety of celecoxib has been investigated, limited data are available on complications affecting the entire (upper and lower) gastrointestinal (GI) tract, with no patient-level pooled analyses of upper and lower GI outcomes available. We therefore evaluated the upper and l...

Subject

Medicine

Internal medicine

Meta-analysis

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