Pleiotropic genes for metabolic syndrome and inflammation

T. Kraja, Aldi; I. Chasman, Daniel; E. North, Kari; P. Reiner, Alex; R. Yanek, Lisa; O. Kilpeläinen, Tuomas; A. Smith, Jennifer; Dehghan, Abbas; Dupuis, Josée; D. Johnson, Andrew; F. Feitosa, Mary; Tekola‐Ayele, Fasil; Y. Chu, Audrey; M. Nolte, Ilja; Dastani, Zari; P. Morris, Andrew; A. Pendergrass, Sarah; V. Sun, Yan; D. Ritchie, Marylyn; Vaez, Ahmad; Lin, Honghuang; Ligthart, Symen; Marullo, Letizia; Rohde, Rebecca; Shao, Yaming; A. Ziegler, Mark; Kyung Im, Hae; B. Schnabel, Renate; Jørgensen, Torben; E. Jørgensen, Marit; Hansen, Torben; Pedersen, Oluf; P. Stolk, Ronald; Snieder, Harold; Hofman, Albert; G. Uitterlinden, André; H. Franco, Oscar; Arfan Ikram, M.; Brent Richards, J.; N. Rotimi, Charles; G. Wilson, James; A. Lange, Leslie; K. Ganesh, Santhi; A. Nalls, Mike; J. Rasmussen‐Torvik, Laura; S. Pankow, James; Coresh, Josef; Tang, Weihong; Linda Kao, W.H.; Boerwinkle, Eric; C. Morrison, Alanna; M. Ridker, Paul; M. Becker, Diane; I. Rotter, Jerome; L. R. Kardia, Sharon; J. F. Loos, Ruth; G. Larson, Martin; Hsu, Yi-Hsiang; A. Province, Michael; P. Tracy, Russell; F. Voight, Benjamin; Vaidya, Dhananjay; J. O’Donnell, Christopher; J. Benjamin, Emelia; Z. Alizadeh, Behrooz; Prokopenko, Inga; B. Meigs, James; B. Borecki, Ingrid

doi:10.1016/j.ymgme.2014.04.007

Public

Pleiotropic genes for metabolic syndrome and inflammation

Published in Molecular Genetics and Metabolism • May 9, 2014

Authors:

Aldi T. Kraja

Daniel I. Chasman

Kari E. North

Abstract

Metabolic syndrome (MetS) has become a health and financial burden worldwide. The MetS definition captures clustering of risk factors that predict higher risk for diabetes mellitus and cardiovascular disease. Our study hypothesis is that additional to genes influencing individual MetS risk factors, ...

Subject

Pleiotropy

Genome-wide association study

Metabolic syndrome

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