Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

M. Shanahan, Catherine; H. Crouthamel, Matthew; Kapustin, Alexander; M. Giachelli, Cecilia

doi:10.1161/circresaha.110.234914

Public

Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

Published in Circulation Research • Sep 1, 2011

Authors:

Catherine M. Shanahan

Matthew H. Crouthamel

Alexander Kapustin

Abstract

Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is common in CKD patients and drives vascular calcification. In this article, we review the physiological regulatory me...

Subject

Vascular smooth muscle

Calcification

Kidney disease

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