Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study

C. Morrison, Alanna; A. Bare, Lance; E. Chambless, Lloyd; G. Ellis, Stephen; J. Malloy, Mary; P. Kane, John; S. Pankow, James; J. Devlin, James; T. Willerson, James; Boerwinkle, Eric

doi:10.1093/aje/kwm060

Public

Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study

Published in American Journal of Epidemiology • Apr 18, 2007

Authors:

Alanna C. Morrison

Lance A. Bare

Lloyd E. Chambless

Abstract

Recent studies have evaluated whether incorporating nontraditional risk factors improves coronary heart disease (CHD) prediction models. This 1986-2001 US study aggregated the contribution of multiple single nucleotide polymorphisms into a genetic risk score (GRS) and assessed whether the GRS plus t...

Subject

Framingham Risk Score

Medicine

Atherosclerosis Risk in Communities

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