The Effects of Particulate Wear Debris, Cytokines, and Growth Factors on the Functions of MG-63 Osteoblasts

Vermes, Csaba; Chandrasekaran, Raman; J. Jacobs, Joshua; O. Galante, Jorge; A. Roebuck, Kenneth; T. Glant, Tibor

doi:10.2106/00004623-200102000-00007

Public

The Effects of Particulate Wear Debris, Cytokines, and Growth Factors on the Functions of MG-63 Osteoblasts

Published in Journal of Bone and Joint Surgery • Feb 1, 2001

Authors:

Csaba Vermes

Raman Chandrasekaran

Joshua J. Jacobs

Abstract

BACKGROUND: Particle-challenged cells release cytokines, chemokines, and eicosanoids, which contribute to periprosthetic osteolysis. The particle-induced activation of macrophages and monocytes has been extensively studied, but only limited information is available on the response of osteoblasts to ...

Subject

Particulates

Debris

Cell biology

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