IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

Molet, Sophie; Hamid, Qutayba; Davoineb, Francis; Nutku, Esra; Tahaa, Rame; Pagé, Nathalie; Olivenstein, Ron; A. Elias, Jack; Chakir, Jamila

doi:10.1067/mai.2001.117929

Public

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

Published in Journal of Allergy and Clinical Immunology • Sep 1, 2001

Authors:

Sophie Molet

Qutayba Hamid

Francis Davoineb

Abstract

BACKGROUND: IL-17 is a cytokine that has been reported to be produced by T lymphocytes. In vitro, IL-17 activates fibro-blasts and macrophages for the secretion of GM-CSF, TNF-alpha, IL-1beta, and IL-6. A number of these cytokines are involved in the airway remodeling that is observed within the lun...

Subject

Bronchoalveolar lavage

Cytokine

Immunocytochemistry

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