Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.

X, Xu; Z, Fan; L, Kang; J, Han; C, Jiang; X, Zheng; Z, Zhu; H, Jiao; J, Lin; K, Jiang; L, Ding; H, Zhang; L, Cheng; H, Fu; Y, Song; Y, Jiang; J, Liu; R, Wang; N, Du; Q, Ye

doi:10.1172/jci64265

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Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.

Shared by NobleBlocks on Jan 16, 2013 • 12:00 AM UTC

Authors:

Xu X

Fan Z

Kang L

Abstract

MicroRNAs (miRNAs) have been shown to be dysregulated in virus-related cancers; however, miRNA regulation of virus-related cancer development and progression remains poorly understood. Here, we report that miR-148a is repressed by hepatitis B virus (HBV) X protein (HBx) to promote cancer growth and ...

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