A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis

C. van Santvoort, Hjalmar; G. Besselink, Marc; J. Bakker, Olaf; Sijbrand Hofker, H.; A. Boermeester, Marja; H.C. Dejong, Cornelis; van Goor, Harry; F. Schaapherder, Alexander; H.J. van Eijck, Casper; L. Bollen, Thomas; van Ramshorst, Bert; B. Nieuwenhuijs, Vincent; Timmer, Robin; S. Laméris, Johan; M. Kruyt, Philip; R. Manusama, Eric; van der Harst, Erwin; P. van der Schelling, George; M. Karsten, Tom; J. Hesselink, E.; JHM van Laarhoven, Cornelis; Rosman, Camiel; Bosscha, Koop; J. de Wit, Ralph; P. J. Houdijk, Alexander; S. van Leeuwen, Maarten; Buskens, Erik; G. Gooszen, Hein

doi:10.1056/nejmoa0908821

Public

A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis

Published in New England Journal of Medicine • Apr 21, 2010

Authors:

Hjalmar C. van Santvoort

Marc G. Besselink

Olaf J. Bakker

Abstract

BACKGROUND: Necrotizing pancreatitis with infected necrotic tissue is associated with a high rate of complications and death. Standard treatment is open necrosectomy. The outcome may be improved by a minimally invasive step-up approach. METHODS: In this multicenter study, we randomly assigned 88 pat...

Subject

Medicine

Surgery

Percutaneous

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