Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.

T, Hayashi; H, Oshima; T, Mashima; T, Nagata; M, Katahira; M, Kinoshita

doi:10.1093/nar/gku382

Public

Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.

Shared by NobleBlocks on May 6, 2014 • 12:00 AM UTC

Authors:

Hayashi T

Oshima H

Mashima T

Abstract

It is a central issue to elucidate the new type of molecular recognition accompanied by a global structural change of a molecule upon binding to its targets. Here we investigate the driving force for the binding of R12 (a ribonucleic acid aptamer) and P16 (a partial peptide of a prion protein) durin...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!