Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia

Liu, Hui; Heath, Simon; Sobin, Christina; L. Roos, Johannes; L. Galke, Brandi; L. Blundell, Maude; Lenane, Marge; Robertson, Brian; M. Wijsman, Ellen; L. Rapoport, Judith; A. Gogos, Joseph; Karayiorgou, Maria

doi:10.1073/pnas.042700699

Public

Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia

Published in Proceedings of the National Academy of Sciences • Mar 12, 2002

Authors:

Hui Liu

Simon Heath

Christina Sobin

Abstract

The location of a schizophrenia susceptibility locus at chromosome 22q11 has been suggested by genome-wide linkage studies. Additional support was provided by the observation of a higher-than-expected frequency of 22q11 microdeletions in patients with schizophrenia and the demonstration that approxi...

Subject

Locus (genetics)

Variation (astronomy)

Schizophrenia (object-oriented programming)

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