A Comparison of Hirudin with Heparin in the Prevention of Restenosis after Coronary Angioplasty

W. Serruys, Patrick; R. Herrman, Jean‐Paul; Simon, Rüdiger; Rutsch, Wolfgang; Bode, Christoph; Laarman, GertJan; van Dijk, Rene; A. van den Bos, Arjan; A. Umans, Victor; A.A. Fox, Keith; Close, Philip; W. Deckers, Jaap

doi:10.1056/nejm199509213331203

Public

A Comparison of Hirudin with Heparin in the Prevention of Restenosis after Coronary Angioplasty

Published in New England Journal of Medicine • Sep 21, 1995

Authors:

Patrick W. Serruys

Jean‐Paul R. Herrman

Rüdiger Simon

Abstract

BACKGROUND: The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty. We compared two regimens of recombinant hirudin with heparin. METHODS: W...

Subject

Hirudin

Medicine

Restenosis

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