A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. Helvetica Investigators.

PW, Serruys; JP, Herrman; R, Simon; W, Rutsch; C, Bode; GJ, Laarman; Dijk R, van; den Bos AA, van; VA, Umans; KA, Fox

doi:10.1056/nejm199509213331203

Public

A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. Helvetica Investigators.

Shared by NobleBlocks on Sep 1, 1995 • 12:00 AM UTC

Authors:

Serruys PW

Herrman JP

Simon R

Abstract

Background The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty. We compared two regimens of recombinant hirudin with heparin.Methods We r...

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