Long-term effects of routine morphine infusion in mechanically ventilated neonates on children’s functioning: Five-year follow-up of a randomized controlled trial

de Graaf, Joke; A. van Lingen, Richard; H. P. Simons, Sinno; Anand, K.J.S.; J. Duivenvoorden, Hugo; Weisglas‐Kuperus, Nynke; Roofthooft, Daniëlla; J.M. Groot Jebbink, Liesbeth; Veenstra, Ravian; Tibboel, Dick; van Dijk, Monique

doi:10.1016/j.pain.2011.02.017

Public

Long-term effects of routine morphine infusion in mechanically ventilated neonates on children’s functioning: Five-year follow-up of a randomized controlled trial

Published in Pain • Mar 13, 2011

Authors:

Joke de Graaf

Richard A. van Lingen

Sinno H. P. Simons

Abstract

Newborns on ventilatory support often receive morphine to induce analgesia. Animal experiments suggest that this may impair subsequent cognitive and behavioral development. There are sparse human data on long-term effects of neonatal morphine. We aimed to investigate the effects of continuous morphi...

Subject

Morphine

Neurocognitive

Medicine

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