HDAC6 Expression Is Correlated with Better Survival in Breast Cancer

Zhang, Zhenhuan; Yamashita, Hiroko; Toyama, Tatsuya; Sugiura, Hiroshi; Omoto, Yoko; Ando, Yoshiaki; Mita, Keiko; Hamaguchi, Maho; Hayashi, Shin‐ichi; Iwase, Hirotaka

doi:10.1158/1078-0432.ccr-04-0455

Public

HDAC6 Expression Is Correlated with Better Survival in Breast Cancer

Published in Clinical Cancer Research • Oct 15, 2004

Authors:

Zhenhuan Zhang

Hiroko Yamashita

Tatsuya Toyama

Abstract

PURPOSE: The structure and function of chromatin can be altered by modifications to histone. Histone acetylation in vivo is a dynamic reversible process governed by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HDAC6 is a unique isoform among the HDACs, and a gene expression pa...

Subject

Breast cancer

Cancer research

Biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!