Estrogen Therapy and Coronary-Artery Calcification

E. Manson, JoAnn; Allison, Matthew; E. Rossouw, Jacques; Jeffrey Carr, J.; D. Langer, Robert; Hsia, Judith; H. Kuller, Lewis; B. Cochrane, Barbara; Hunt, Julie; Ludlam, Shari; Pettinger, Mary; Gass, Margery; L. Margolis, Karen; Nathan, Lauren; K. Ockene, Judith; L. Prentice, Ross; A. Robbins, John; L. Stefanick, Marcia

doi:10.1056/nejmoa071513

Public

Estrogen Therapy and Coronary-Artery Calcification

Published in New England Journal of Medicine • Jun 20, 2007

Authors:

JoAnn E. Manson

Matthew Allison

Jacques E. Rossouw

Abstract

BACKGROUND: Calcified plaque in the coronary arteries is a marker for atheromatous-plaque burden and is predictive of future risk of cardiovascular events. We examined the relationship between estrogen therapy and coronary-artery calcium in the context of a randomized clinical trial. METHODS: In our...

Subject

Medicine

Placebo

Odds ratio

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