Genetic Susceptibility for Human Familial Essential Hypertension in a Region of Homology with Blood Pressure Linkage on Rat Chromosome 10

Julier, Cécile; Délepine, Marc; Keavney, Bernard; D. Terwilliger, Joseph; Davis, Sean; E. Weeks, Daniel; Anh Bùi, Thuỳ; Jeunemaı̂tre, Xavier; Velho, Gilberto; Froguel, Philippe; J. Ratcliffe, Peter; Corvol, Pierre; Soubrier, Florent; Mark Lathrop, G.

doi:10.1093/hmg/6.12.2077

Public

Genetic Susceptibility for Human Familial Essential Hypertension in a Region of Homology with Blood Pressure Linkage on Rat Chromosome 10

Published in Human Molecular Genetics • Nov 1, 1997

Authors:

Cécile Julier

Marc Délepine

Bernard Keavney

Abstract

Hypertension is a significant risk factor for heart attack and stroke and represents a major public health burden because of its high prevalence (e.g. 15-20% of the European and American populations). Although blood pressure is known to have a strong genetic determination, the genes responsible for ...

Subject

Biology

Genetics

Locus (genetics)

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