Pretransplant Sensitization Against Angiotensin II Type 1 Receptor Is a Risk Factor for Acute Rejection and Graft Loss

Giral, Magali; Foucher, Yohann; Dufay, Alexandre; Duong Van Huyen, J.P.; Renaudin, Karine; Moreau, Aurélie; Philippe, Aurélie; Hegner, B.; Dechend, Ralf; Heidecke, Harald; Brouard, Sophie; Cesbron, Anne; Castagnet, Sophie; Devys, Anne; Paul Soulillou, Jean; Dragun, Duska

doi:10.1111/ajt.12397

Public

Pretransplant Sensitization Against Angiotensin II Type 1 Receptor Is a Risk Factor for Acute Rejection and Graft Loss

Published in American Journal of Transplantation • Aug 6, 2013

Authors:

Magali Giral

Yohann Foucher

Alexandre Dufay

Abstract

The angiotensin II type 1 receptor (AT1R) is an emerging target of functional non-HLA antibodies (Ab). We examined the potential of determining the degree of presensitization against AT1R as a risk factor for graft survival and acute rejection (AR). The study included 599 kidney recipients between 1...

Subject

Medicine

Angiotensin II

Risk factor

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