Intensive Dose-Dense Compared With Conventionally Scheduled Preoperative Chemotherapy for High-Risk Primary Breast Cancer

Untch, Michael; Möbus, Volker; Kuhn, Walther; R. Muck, B.; Thomssen, Christoph; Bauerfeind, Ingo; Harbeck, Nadia; Werner, Christoph; Lebeau, Annette; Schneeweiß, Andreas; Kahlert, S.; Koch, Franz; Ulrich Petry, Karl; Wallwiener, D.; Kreienberg, R.; Albert, Ute‐Susann; Lück, Hans‐Joachim; Hinke, Axel; Jänicke, F.; E. Konecny, Gottfried

doi:10.1200/jco.2008.20.3133

Public

Intensive Dose-Dense Compared With Conventionally Scheduled Preoperative Chemotherapy for High-Risk Primary Breast Cancer

Published in Journal of Clinical Oncology • Apr 14, 2009

Authors:

Michael Untch

Volker Möbus

Walther Kuhn

Abstract

PURPOSE: To compare preoperative intense dose-dense (IDD) chemotherapy with conventionally scheduled preoperative chemotherapy in high-risk primary breast cancer (BC). PATIENTS AND METHODS: In this randomized phase III trial a total of 668 eligible primary BC patients stratified for tumors > or = 3 ...

Subject

Medicine

Epirubicin

Internal medicine

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