The Chemokine SDF‐1/CXCL12 Contributes to T Lymphocyte Recruitment in Human Pre‐ovulatory Follicles and Coordinates with Lymphocytes to Increase Granulosa Cell Survival and Embryo Quality

Kryczek, Ilona; Frydman, Nelly; Gaudin, Françoise; Krzysiek, Roman; Fanchin, Rénato; Émilie, Dominique; Chouaı̈b, Salem; Zou, Weiping; Machelon, Véronique

doi:10.1111/j.1600-0897.2005.00307.x

Public

The Chemokine SDF‐1/CXCL12 Contributes to T Lymphocyte Recruitment in Human Pre‐ovulatory Follicles and Coordinates with Lymphocytes to Increase Granulosa Cell Survival and Embryo Quality

Published in American Journal of Reproductive Immunology • Oct 7, 2005

Authors:

Ilona Kryczek

Nelly Frydman

Françoise Gaudin

Abstract

We investigated the production and the role of the chemokine stromal cell-derived factor-1 (SDF-1/CXCL12) in pre-ovulatory follicles of women undergoing in vitro fertilization. We detected CXCL12 and its receptor CXCR4 by flow cytometry, western blotting and RT-PCR. We tested cell migration in Trans...

Subject

CXCR4

Biology

Stromal cell

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