Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

Clarke, Colin; F. Madden, Stephen; Doolan, Padraig; Aherne, Sinéad; Joyce, Helena; O’Driscoll, Lorraine; M. Gallagher, William; T. Hennessy, Bryan; Moriarty, M.; Crown, John; Kennedy, Susan; Clynes, Martin

doi:10.1093/carcin/bgt208

Public

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

Published in Carcinogenesis • Jun 5, 2013

Authors:

Colin Clarke

Stephen F. Madden

Padraig Doolan

Abstract

Weighted gene coexpression network analysis (WGCNA) is a powerful 'guilt-by-association'-based method to extract coexpressed groups of genes from large heterogeneous messenger RNA expression data sets. We have utilized WGCNA to identify 11 coregulated gene clusters across 2342 breast cancer samples ...

Subject

Biology

Breast cancer

Gene

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