Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg -BPI

González‐Aravena, Marcelo; Gueguen, Yannick; Destoumieux‐Garzón, Delphine; Romestand, Bernard; Fiévet, Julie; Pugnière, Martine; Roquet, Françoise; Escoubas, Jean-Michel; Vandenbulcke, Franck; Levy, Ofer; Sauné, Laure; Bulet, Philippe; Bachère, Evelyne

doi:10.1073/pnas.0702281104

Public

Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg -BPI

Published in Proceedings of the National Academy of Sciences • Oct 26, 2007

Authors:

Marcelo González‐Aravena

Yannick Gueguen

Delphine Destoumieux‐Garzón

Abstract

A cDNA sequence with homologies to members of the LPS-binding protein and bactericidal/permeability-increasing protein (BPI) family was identified in the oyster Crassostrea gigas. The recombinant protein was found to bind LPS, to display bactericidal activity against Escherichia coli, and to increas...

Subject

Crassostrea

Biology

Oyster

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