Early Lactate-Guided Therapy in Intensive Care Unit Patients: A Multicenter, Open-Label, Randomized Controlled Trial

C. Jansen, Tim; van Bommel, Jasper; J Schoonderbeek, F; J Sleeswijk Visser, Steven; M. van der Klooster, Johan; Pinto de Lima, Alex; P. Willemsen, Sten; Bakker, Jan

doi:10.1164/rccm.200912-1918oc

Public

Early Lactate-Guided Therapy in Intensive Care Unit Patients: A Multicenter, Open-Label, Randomized Controlled Trial

Published in American Journal of Respiratory and Critical Care Medicine • May 12, 2010

Authors:

Tim C. Jansen

Jasper van Bommel

F J Schoonderbeek

Abstract

RATIONALE: It is unknown whether lactate monitoring aimed to decrease levels during initial treatment in critically ill patients improves outcome. OBJECTIVES: To assess the effect of lactate monitoring and resuscitation directed at decreasing lactate levels in intensive care unit (ICU) patients admi...

Subject

Medicine

Hyperlactatemia

Intensive care unit

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