Distinct Genetic Influences on Cortical Surface Area and Cortical Thickness

S. Panizzon, Matthew; Fennema‐Notestine, Christine; T. Eyler, Lisa; L. Jernigan, Terry; Prom‐Wormley, Elizabeth; C. Neale, Michael; C. Jacobson, Kristen; J. Lyons, Michael; D. Grant, Michael; E. Franz, Carol; Xian, Hong; T. Tsuang, Ming; Fischl, Bruce; J. Seidman, Larry; M. Dale, Anders; S. Kremen, William

doi:10.1093/cercor/bhp026

Public

Distinct Genetic Influences on Cortical Surface Area and Cortical Thickness

Published in Cerebral Cortex • Mar 18, 2009

Authors:

Matthew S. Panizzon

Christine Fennema‐Notestine

Lisa T. Eyler

Abstract

Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical volume. Given that cortical volume is a product of thickness and surface area, it is plausible that measures of volume capture at least 2 distinct...

Subject

Heritability

Endophenotype

Genetic architecture

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