Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease

Ramachandran, Surya; Venugopal, Anila; Raman Kutty, V.; Anandan, Vinitha; Divya, G.; Chitrasree, V; Mullassari, Ajit; S Pratapchandran, N; Santosh, Kagathur; Radhakrishna Pillai, M.; Sudha Kartha, C.

doi:10.1186/1475-2840-13-38

Public

Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease

Published in Cardiovascular Diabetology • Feb 7, 2014

Authors:

Surya Ramachandran

Anila Venugopal

V. Raman Kutty

Abstract

AIMS/HYPOTHESIS: Cyclophilin A, an immunophilin is secreted from human monocytes activated by high glucose. Given its role as an inflammatory mediator of vascular tissue damage associated with inflammation and oxidative stress, we examined plasma levels of cyclophilin A in normal healthy volunteers ...

Subject

Medicine

Angiology

Diabetes mellitus

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