Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology

Helb, Danica; Jones, Martin; Story‐Roller, Elizabeth; Boehme, Catharina; Wallace, Ellen; Ho, Ken; Kop, JoAnn; R. Owens, Michelle; Rodgers, Richard; P. Banada, Padmapriya; Safi, Hassan; Blakemore, Robert; Thị Ngọc Lan, Nguyễn; C. Jones‐López, Edward; H. Levi, Michael; Burday, Michele; Ayakaka, Irene; D. Mugerwa, Roy; McMillan, Bill; S. Winn-Deen, Emily; A. Christel, L.; J. Dailey, Peter; D. Perkins, Mark; H. Persing, David; Alland, David

doi:10.1128/jcm.01463-09

Public

Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology

Published in Journal of Clinical Microbiology • Oct 28, 2009

Authors:

Danica Helb

Martin Jones

Elizabeth Story‐Roller

Abstract

Current nucleic acid amplification methods to detect Mycobacterium tuberculosis are complex, labor-intensive, and technically challenging. We developed and performed the first analysis of the Cepheid Gene Xpert System's MTB/RIF assay, an integrated hands-free sputum-processing and real-time PCR syst...

Subject

Tuberculosis

Sputum

Mycobacterium tuberculosis

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