Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

D. Querec, Troy; Bennouna, Soumaya; Alkan, Sefik; Laouar, Yasmina; Gorden, Keith; A. Flavell, Richard; Akira, Shizuo; Ahmed, Rafi; Pulendran, Bali

doi:10.1084/jem.20051720

Public

Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

Published in The Journal of Experimental Medicine • Feb 6, 2006

Authors:

Troy D. Querec

Soumaya Bennouna

Sefik Alkan

Abstract

The live attenuated yellow fever vaccine 17D (YF-17D) is one of the most effective vaccines available, with a 65-yr history of use in >400 million people globally. Despite this efficacy, there is presently no information about the immunological mechanisms by which YF-17D acts. Here, we present data ...

Subject

Yellow fever vaccine

Immunology

Immune system

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