Molecular and Pharmacological Determinants of the Therapeutic Response to Artemether-Lumefantrine in Multidrug-Resistant Plasmodium falciparum Malaria

N. Price, Ric; Uhlemann, Anne‐Catrin; van Vugt, Michèle; Brockman, Al; Hutagalung, Robert; Nair, Shalini; A Nash, Daniel; Singhasivanon, Pratap; Anderson, Tim; Krishna, Sanjeev; J. White, Nicholas; Nosten, François

doi:10.1086/503423

Public

Molecular and Pharmacological Determinants of the Therapeutic Response to Artemether-Lumefantrine in Multidrug-Resistant Plasmodium falciparum Malaria

Published in Clinical Infectious Diseases • May 2, 2006

Authors:

Ric N. Price

Anne‐Catrin Uhlemann

Michèle van Vugt

Abstract

BACKGROUND: Our study examined the relative contributions of host, pharmacokinetic, and parasitological factors in determining the therapeutic response to artemether-lumefantrine (AL). METHODS: On the northwest border of Thailand, patients with uncomplicated Plasmodium falciparum malaria were enroll...

Subject

Artemether/lumefantrine

Artemether

Plasmodium falciparum

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