Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

A. Madhi, Shabir; A. Cunliffe, Nigel; Duncan Steele, A.; Witte, Desirée; Kirsten, Mari; Louw, Cheryl; Ngwira, Bagrey; C. Victor, John; Gillard, Paul; Cheuvart, Brigitte; Htay Han, Htay; M. Neuzil, Kathleen

doi:10.1056/nejmoa0904797

Public

Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants

Published in New England Journal of Medicine • Jan 27, 2010

Authors:

Shabir A. Madhi

Nigel A. Cunliffe

A. Duncan Steele

Abstract

BACKGROUND: Rotavirus is the most common cause of severe gastroenteritis among young children worldwide. Data are needed to assess the efficacy of the rotavirus vaccine in African children. METHODS: We conducted a randomized, placebo-controlled, multicenter trial in South Africa (3166 infants; 64.1%...

Subject

Medicine

Rotavirus vaccine

Rotavirus

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