A Map of the Interactome Network of the Metazoan <i>C. elegans</i>

Li, Siming; M. Armstrong, Christopher; Bertin, Nicolas; Ming Ge, Hui; Milstein, Stuart; Boxem, Mike; Vidalain, Pierre‐Olivier; Han, Jing-Dong; Chesneau, Alban; Hao, Tong; S. Goldberg, Debra; Li, Ning; Martinez, Monica; Rual, Jean‐François; Lamesch, Philippe; Xu, Lai; Tewari, Muneesh; L. Wong, S.; V. Zhang, Lan; F. Berriz, Gabriel; Jacotot, Laurent; Vaglio, Philippe; Reboul, Jérôme; Hirozane-Kishikawa, Tomoko; Li, Qianru; W. Gabel, Harrison; Elewa, Ahmed; Baumgartner, Bridget; J. Rose, Debra; Yu, Haiyuan; Bosak, Stephanie; Sequerra, Reynaldo; Fraser, Andrew; E. Mango, Susan; M. Saxton, William; Strome, Susan; van den Heuvel, Sander; Piano, Fabio; Vandenhaute, Jean; Sardet, Claude; Gerstein, Mark; Doucette‐Stamm, Lynn; C. Gunsalus, Kristin; Wade Harper, J.; E. Cusick, M.; P. Roth, Frederick; E. Hill, David; Vidal, Marc

doi:10.1126/science.1091403

Public

A Map of the Interactome Network of the Metazoan C. elegans

Published in Science • Jan 5, 2004

Authors:

Siming Li

Christopher M. Armstrong

Nicolas Bertin

Abstract

To initiate studies on how protein-protein interaction (or "interactome") networks relate to multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans interactome network. Starting with a subset of metazoan-specific proteins, more than 4000 interactions were identified f...

Subject

Interactome

In silico

Phenome

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